No change of instance-profile possible

Hello together,

I want to Change some Buffer Parameters in the instance-Profile but after importing the profiles of all active Servers, I get the follpwing message:

You have no authorization to Change and Display profiles could not be activated

Changing Parameters and activating the Profile is also not possible.

I have also checked the file rights to the profile-directory but found no problems.Anyone an idea?

Best regards,

Mathias